11 December 2018 | NewsVaccine safety in Australia AusVaxSafety summary report 2016-17Read the full article
AusVaxSafety is a national, collaborative active vaccine safety surveillance initiative led by NCIRS and funded by the Australian Government Department of Health.
Vaccines prevent millions of deaths worldwide each year and have dramatically reduced deaths and disability from infectious diseases in Australia. While we continue to receive these benefits through immunisation programs, it is vital that we monitor vaccines to ensure continuing safety and to maintain public confidence in immunisation.
An adverse event following immunisation is any unfavourable and unintended symptom in a person who has been given a vaccine. In many cases, adverse events reported in the days or weeks after vaccination have nothing to do with the vaccine itself, but are a 'coincidence'. AusVaxSafety monitors all adverse events, even those not caused by the vaccine. By monitoring all adverse events occurring after vaccination, and investigating those that are unusual, any unexpected events will be identified early to allow effective public health action.
AusVaxSafety monitors the safety of vaccines in three ways:
SmartVax and Vaxtracker are software programs run by general practitioners and immunisation clinics that send an SMS or email to patients or parents following a vaccination. De-identified information from SmartVax and Vaxtracker are combined and monitored by AusVaxSafety to detect possible safety signals for vaccines.
SmartVax and Vaxtracker are used by more than 200 sentinel surveillance sites including general practices, immunisation clinics, hospital- and community-based clinics, and Aboriginal Medical Services spread across all Australian states and territories.
AusVaxSafety monitors the safety of pertussis, zoster and influenza vaccines via participants recruited in sentinel surveillance sites nationwide.
AEFI-CAN is a formal collaboration between state- and territory-based immunisation specialist clinics. It includes representatives from the Department of Health (Office of Health Protection and the Therapeutic Goods Administration) and most jurisdictional health departments. It is coordinated by Victoria’s state-based surveillance body SAEFVIC (at the Murdoch Children’s Research Institute) in collaboration with NCIRS.
As a national network, AEFI-CAN works collaboratively with all stakeholders to develop a consistent and robust national approach to serious and/or severe AEFI. This involves creating standardised clinical protocols and facilitating uniform AEFI clinical follow up through a national AEFI-CAN clinical database.
AEFI-CAN holds regular teleconferences with members, which provides a platform for a diverse group of vaccine safety clinical experts and policy makers to discuss a range of clinically relevant issues, and has helped strengthen collaborative working relationships among members.
NPS MedicineInsight collects de-identified patient information from over 600 general practices. The Telethon Kids Institute (TKI), NCIRS and NPS are combining strengths to investigate the safety of the zoster (shingles) vaccine in hundreds of thousands of older Australians.
Data is analysed by NCIRS in collaboration with colleagues at TKI, who use statistical methods to automatically detect safety signals. Regular reports (weekly to monthly) are provided to the Australian Government Department of Health Immunisation Branch and the Therapeutic Goods Administration (TGA), and shared with participating state and territory health departments. Other specific studies are undertaken as required.
During 2018, AusVaxSafety surveillance is being conducted for the following vaccines and age groups:
Surveillance will be expanded to other vaccines and age groups in the near future.
AusVaxSafety is made possible by the contributions of our collaborators along with state and territory governments:
For further information on AusVaxSafety:
NCIRS, Kids Research, Sydney Children’s Hospitals Network, Cnr Hawkesbury Rd & Hainsworth St, Westmead Locked Bag 4001, Westmead NSW 2145 Tel (612) 9845 1433 | Fax (612) 9845 1418 | ABN 53 188 579 090
We acknowledge that the National Centre for Immunisation Research & Surveillance (NCIRS) is on the land of the traditional owners the Aboriginal and Torres Strait Islander peoples, the First Australians, and recognise their culture, history, diversity and their deep connection to the land. Together, through research and partnership, we aim to move to a place of equity for all. NCIRS also acknowledges and pays respect to other Aboriginal and Torres Strait Islander nations from which our research, staff and community are drawn.
Our website meets the criteria for credibility and content as defined by the Global Advisory Committee on Vaccine Safety.