Diphtheria and tetanus toxoids and acellular pertussis (DTPa) containing vaccines GRADE assessments

ATAGI recommendations

Use of DT5aP-hepB-IPV-Hib(PRP-OMP) versus DT3aP-HBV-IPV-Hib(PRP-TT) in infants aged 6 weeks to 10 years

Diphtheria and tetanus toxoids and acellular pertussis, inactivated poliovirus, Haemophilus b conjugate and hepatitis B vaccine (Vaxelis, DT5aP-hepB-IPV-Hib[PRP-OMP])

Coversheet on evidence assessment by ATAGI using the GRADE framework for DT5aP-hepB-IPV-Hib(PRP-OMP)) in infants aged 6 weeks to 10 years

GRADE assessment for DT5aP-hepB-IPV-Hib(PRP-OMP)

Compared against DT3aP-HBV-IPV-Hib(PRP-TT) (Infanrix hexa) in infants aged 6 weeks to 10 years

Note: These GRADE documents should be read as a supplement to Australian Immunisation Handbook recommendations. View the related disease chapters in the Handbook here:

• Diphtheria
• Haemophilus influenzae type b (Hib)
• Hepatitis B
• Pertussis (whooping cough)
• Poliomyelitis
• Tetanus